Integrative genomics in cardiovascular medicine.
نویسندگان
چکیده
Integrative genomics studies have greatly advanced our understanding of cardiovascular pathophysiology over the last decade. Here, we highlight the strengths and challenges of this cutting-edge approach and provide examples where novel insights have arisen through the integration of multi-level genomic information and cardiac physiology. Going forward, the integration of comprehensive next-generation sequencing data sets with quantitative phenotypes at the molecular, cellular, and whole-heart level using advanced modelling approaches provides an unprecedented opportunity for cardiovascular science.
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ورودعنوان ژورنال:
- Cardiovascular research
دوره 97 4 شماره
صفحات -
تاریخ انتشار 2013